CYP4B1 allele nomenclature

*Allele*	*Protein*	Nucleotide changes, cDNA	*Effect*	*Enzyme activity*		*References*
*Allele*	*Protein*	Nucleotide changes, cDNA	*Effect*	*In_vivo*	*In_vitro*	*References*
CYP4B11*	CYP4B1.1	None	None	Normal	Normal
CYP4B12A*		881_882delAT; 993G>A; 1018C>T; 1123C>T	294Frameshift			Lo-Guidice et al, 2002
CYP4B12B*		881_882delAT; 993G>A; 1018C>T	294Frameshift			Hiratsuka et al., 2004
CYP4B13*	CYP4B1.3	517C>T	R173W			Lo-Guidice et al, 2002
CYP4B14*	CYP4B1.4	964A>G	S322G			Lo-Guidice et al, 2002
CYP4B15*	CYP4B1.5	993G>A	M331I			Lo-Guidice et al, 2002
CYP4B16*	CYP4B1.6	517C>T; 1033G>A	R173W; V345I			Hiratsuka et al., 2004
CYP4B17*		See CYP4B12B*

Changes made since the last update (13-Nov-2007) are marked in red.

Links to the NCBI dbSNP homepage are available for functional SNPs when present in NCBI's database.

Nucleotide variations in bold are the major SNPs/alterations responsible for the phenotype of the corresponding allele.

Please contact Dr. Jean-Marc Lo-Guidice for more information about CYP4B1*2, *3, *4 and *5 alleles.