The Pharmacogene Variation (PharmVar) Consortium is a central repository for pharmacogene (PGx) variation that focuses on haplotype structure and allelic variation. The information in this resource facilitates the interpretation of pharmacogenetic test results to guide precision medicine.
The Pharmacogene Variation (PharmVar) Consortium is the new home for PGx gene nomenclature and serves as a centralized "Next-Generation" Pharmacogene Variation data repository. After more than 15 years, the Human Cytochrome P450 (CYP) Allele Nomenclature website has been transitioned from its original location at the Karolinska Institute in Sweden to Children's Mercy in Kansas City, USA. A new interactive database is under development and will be a launched in Q4 2017. The first version of the PharmVar database will contain the high-priority CYP2C9, CYP2C19 and CYP2D6 genes; other P450 genes will be transferred to PharmVar within the first year of the project (once a gene is transferred into PharmVar, it will receive legacy status on the Nomenclature website). Other PGx genes including clinically actionable CPIC genes will be added in the future.
Original content from the cypalleles.ki.se site is available through the archived home page